Analytical

Advances in Analytical Ion Mobility Separations (#61)

Over the last decade, ion mobility spectrometry coupled to mass spectrometry (IMS/MS) has evolved from an academic interest to a broadly useful tool for complex biological and environmental analyses. This transition has been enabled by MS equipment vendors introducing various IMS/MS products, which has massively expanded and diversified the IMS community and stimulated application development. Concomitantly, the power of IMS was greatly enhanced by the rise of methods beyond the original linear drift-tube paradigm, including traveling-wave IMS and, most importantly, differential IMS or FAIMS based on the derivative of ion mobility with respect to the electric field intensity. This symposium, the first on IMS at PacifiChem, will feature the latest work on both stand-alone IMS and IMS/MS from academia, industry, and government sectors. The opening session will focus on the advances in IMS technology, particularly emphasizing the new nonlinear and extreme-resolution approaches that push the field frontier. The following sessions will cover the challenging applications of IMS and IMS/MS across major analytical areas, such as proteomics, metabolomics, pharmaceutical studies, structural biology, security screening, atmospheric science, environmental monitoring, and product quality control. The important aspect of IMS data interpretation and associated fundamental investigations and computational techniques will also be addressed.
Last update: Dec 28, 2015