Frontiers of Iron Chemistry in Biology (#268)

Iron is the most essential metal ion in vivo, and iron-containing proteins play crucial roles in various kinds of biological processes including respiratory system, metabolism, energy production and gene regulation. To understand these biological processes, or our life, in the molecular level, the chemical characterization of various kinds of iron-containing proteins is required. Particularly, chemistry of iron showing the specific functions in proteins is quite interesting and recent progress in molecular biology revealed that a number of new iron-containing proteins are essential for various kinds of our biological systems. Thus, the chemical characterization of iron-containing proteins is a key to understand functional significance of iron in vivo, but it has not yet been fully understood. In this symposium, we focus on some iron-containing proteins essential for life and examine their functional and structural significance in the biological systems by the sophisticated chemical approaches to proteins. Based on the intensive discussion from various aspects of iron-containing proteins, we will provide a general view of the researches to clarify the essential roles of iron in proteins, and the future studies for iron chemistry in biology will be discussed.
Last update: Dec 28, 2015