Biological

Functional Nucleic Acids: Chemistry, Biology, and Materials Applications (#10)

Far beyond their roles in biological information storage, nucleic acids (DNA and RNA) have had major contributions to applications throughout chemistry, biology, and materials science. Despite having only four simple and similar building blocks, nucleic acids can regulate gene expression, recognize ligands and substrates, catalyze chemical reactions, and form macroscopic 3D structures, among other uses. These functional nucleic acids therefore provide an excellent arena for creativity and innovation in many scientific disciplines.

This symposium highlights recent exciting developments in the field of functional nucleic acids and features four sessions whose topics include the following:

(1) mechanistic studies of natural ribozymes and artificial ribozymes and deoxyribozymes
(2) in vitro selection of new RNA/DNA aptamers, ribozymes, and deoxyribozymes
(3) applications of nucleic acids in sensing, pathogen and disease detection, and nanostructure assembly
(4) studies of nucleic acid dynamics, charge migration, damage, and repair
(5) structural and functional studies of non-coding RNAs
(6) chemical and biological analysis of RNA-protein interactions
(7) use of oligonucleotides as therapeutics and nucleic acids as drug targets

Speakers for this symposium include the following people, and many others:

Steven Benner, Foundation for Applied Molecular Evolution
Philip Bevilacqua, Pennsylvania State University
Ichiro Hirao, RIKEN
Gerald Joyce, The Scripps Research Institute
Yi Lu, University of Illinois
Floyd Romesberg, The Scripps Research Institute
Hanadi Sleiman, McGill University
Hiroaki Suga, University of Tokyo
Hiroshi Sugiyama, Kyoto University
Weihong Tan, University of Florida

Last update: Dec 28, 2015