This symposium will highlight recent progress in the area of ultrasensitive bioanalysis. The symposium will comprise of a three-day program. Day one will focus on emerging techniques for controlling small-volume chemistry, especially in the area of biochemical assays and cellular analysis. Specific examples of small volume chemistry and biology include those that take place in lipid vesicles and in droplets made using microfluidics. The development of droplet-based analytical devices for biological analysis, in particular, has witnessed tremendous growth over the past 5 years; we will highlight these recent developments. Day two will emphasize the high sensitivity and high information content analysis of biological samples, using techniques that range from chemical separation to sensitive optical detection and mass spectrometry analysis. Particular emphasis will be given to recent developments in metabolomics as a new paradigm in untargeted bioanalysis. New instrumental advances in separation science and mass spectrometry, multivariate data analysis, and applications in biomarker discovery will be areas of focus for this session. Day three of the symposium will delve into single-cell analysis. Single cells are basic units of living organisms. Over the past decade, the understanding of these basic units of life has grown tremendously, revealing new insights on intracellular processes and new cellular mechanisms. Topics in this session will include component analysis of single cells, cell and material interface, as well as single cell analysis, imaging, and sequencing. |
